Can your lining be too thick for implantation

During a hysteroscopy, a thin scope is gently inserted into the vagina, through the cervix and into the uterus. For the less invasive transvaginal ultrasound, a small device is placed into the vagina that measures sound waves, converting them to images.

However, the ultrasound cannot detect cancer, as the hysteroscopy can. Sometimes endometrium hyperplasia can lead to cancer, so your doctor may want to do a hysteroscopy. Your doctor will determine what level of endometrium thickness is considered abnormal. However, typical normal ranges include 8 to 13 mm, while a uterine lining thicker than 15 mm might reduce your chances of conception. Once your doctor has confirmed during a hysteroscopy or ultrasound that your uterine lining is thick, a prescription medicine can help you thin the endometrium and, as a result, improve chances of conception.

Progestin , a synthetic version of the hormone progesterone, is a common treatment. According to the ACOG, medication is available that can be taken by mouth, in a shot, through an intrauterine device or applied as a vaginal cream.

Healthy fats and dark leafy greens can help with a healthy lining. Additionally, supplements like iron, fish oil, vitamin E, turmeric, and low-dose aspirin may help. Acupuncture is great for improving circulation and is most effective for months with twice-weekly treatments. Just 30 minutes of physical activity helps the body prepare for pregnancy.

Concerned about having an excellent endometrial lining? Then speak with a doctor today. A thin lining could be the reason for infertility or miscarriages. The doctor will first need to look into the root cause of the abnormal uterine lining. From there, there may be some treatment options available. Even during IVF, a thin endometrial lining can lower success rates. The right medical, health, and wellness initiatives can put women with thin endometrial linings on the path to pregnancy. What is the endometrial lining?

What is the role of the endometrial lining in pregnancy? The endometrial implantation window was more uniform, only relating to the timing of progesterone administration that was fixed in this study.

According to common knowledge, embryo quality and endometrial preparation protocol are the two most critical factors which affect the pregnancy outcomes of FET. In all the cycles in this study, at least one good-quality embryo was transferred, which excluded the effect of embryo quality on pregnancy outcome.

Since no minimal cut-off value of endometrium thickness was defined in the original study protocol, the effect of the whole spectrum of endometrial thicknesses in HRT-FET could be studied. Nodal segmentation of endometrial thickness was also not performed. Moreover, the analysis was adjusted for age, the duration of infertility, body mass index, and type of infertility and number cleavage stage embryos or blastocysts of embryos transferred using multivariable logistic regression, all of which contributed to the robust results of this study.

At the same time, this study still had its limitations. As with other relevant clinical studies, an important limitation of this study was the retrospective design, even though we established strict inclusion and exclusion criteria and adjusted confounding factors to control bias through multivariable logistic regression. In addition, the ultrasound monitoring of endometrial thickness might have some measurement imprecision that occur regardless of how experienced the ultrasonographers may be.

There were only 37 patients with an endometrial thickness above the maximum threshold. Which suggests that more HRT-FET cycles especially those with thick endometrium are to be collected in future studies, with the hope of being able to determine an optimal range of endometrial thickness for pregnancy outcomes. In the future, we will continue analyze the data of our center to evaluate the difference between endometrial thickness on the first progesterone day and that on the ET day, and its correlation with the pregnancy outcomes, so as to provide guidance for clinical practice.

In conclusion, in the HRT-FET cycles, a satisfactory live birth rate can be obtained when endometrial thickness is kept within the range of 8. If the endometrial thickness is too thin or too thick, the live birth rate will be reduced. Based on these research results, It is recommended to medical practitioners that transferring embryos should be conducted when the endometrial thickness reaches 8. The risk of preterm labor and neonatal birth weight were not significantly correlated with endometrial thickness.

Browse Subject Areas? Click through the PLOS taxonomy to find articles in your field. Abstract Objective To investigate the impact of endometrial thickness on the embryo transfer ET day on the clinical pregnancy outcomes of frozen-thawed embryo transfer cycles which have undergone hormone replacement therapy HRT-FET.

Results After adjusting for the age, duration of infertility, body mass index BMI , infertility type and number and type of embryos transferred, a significant correlation was observed to be between the endometrial thickness and implantation rates aOR: 1. Conclusions In the HRT-FET cycles, the optimal live birth rate would be obtained when the endometrial thickness remains within the range of 8. Funding: The author s received no specific funding for this work.

Competing interests: All authors have no conflict of interest to declare. Introduction Embryo implantation requires a cross talk between the embryo and the receptive endometrium. Embryo transfer and embryo score Prior to ET, each embryo were was graded according to their developmental speed, degree of fragmentation and the evenness of cleavage sphere.

FET cycle outcomes The primary outcome included the live birth rate, gestational week at the delivery and newborn birth weight. Statistical analysis Statistical analysis was performed using the Empower Stats software base on R language. Download: PPT. Characteristics and periodic features in patients grouped by endometrial thickness on the embryo transfer day.

Table 2. Clinical outcomes in patients grouped by endometrial thickness on the embryo transfer day. Multivariable logistic regression used to evaluate the association between endometrial thickness and pregnancy outcomes In order to control the impact of age, the duration of infertility, BMI and the infertility type primary or secondary on pregnancy outcomes, we performed multivariable logistic regression analysis to evaluate the association between endometrial thickness and pregnancy outcomes.

Table 3. Associations between endometrial thickness and clinical outcomes of HRT-FET cycles using multivariable logistic regression analysis. Curve fitting For continuous variables such as endometrial thickness, the implantation rate, clinical pregnancy rate and live birth rate, the fitted curves are presented in Figs 1 — 3 , respectively.

Fig 1. Fig 2. Fig 3. Threshold effect analysis results The threshold effect analysis of endometrial thickness and the implantation rate, clinical pregnancy rate and live birth rate are presented in Table 4. Table 4. Threshold effect analysis of endometrial thickness and clinical outcomes of HRT-FET cycles using piece-wise linear regression method.

Influence of the delta between the endometrial thickness on the transfer day compared with the thickness at the starting of progesterone day on the clinical outcome Between the endometrial thickness on the transfer day compared with the thickness at the starting of progesterone day, endometrial thickness had no changed cycles, the increased and compaction cycles accounted for Table 5.

Influence of the delta between the endometrial thickness on the transfer day compared with the thickness at the starting of progesterone day on the clinical outcome. Discussion Endometrial receptivity is the key factor affecting the pregnancy outcomes of embryo transfer cycles [ 9 ]. Supporting information. S1 File.

Researchers are still investigating the effects of acupuncture on fertility, but there are some studies that suggest it can improve circulation. Ask your fertility doctor about Viagra suppositories. While Viagra is usually used to improve blood flow to the penis in cases of erectile dysfunction, it can also be used to encourage blood flow to the female pelvic region through the use of vaginal suppositories. Consider your body weight. Women with a low BMI might want to think about gaining a little weight with the help of a nutritionist.

Extra weight can promote pelvic blood flow, and fat cells produce additional estrogen. The goal is to have a normal BMI, which ranges from Investigate nutritional supplements. Reaching the ideal endometrium thickness The IVF process can be demanding: when you are working so hard to try to conceive a baby, you want to do everything in your power to help your chances. Share this on social media:.

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